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Buy psychedelics magic mushrooms online. People in round the world can now order and ship magic mushrooms right to their doorsteps, thanks to a Vancouver activist.

Long-time pot advocate Dana Larsen launched his latest venture, Medicinal Mushroom Dispensary, selling microdoses of psilocybin mushrooms.

“I think that just like cannabis, it is time to start to change the perception of psilocybin mushrooms,” Larsen told CTV News.

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The virtual store sells capsules containing 25mg, 50mg and 100mg of the drug.

Larsen knows his latest business is breaking the law, but said that is the point and he even has lawyers on standby.

“I think it needs to be done openly as a matter of civil disobedience to defy the law in an open way and hopefully that can make the law change, ultimately,” he said.

Denver and Oakland have both recently decriminalized magic mushrooms.

Laren said he wants to help destigmatize the drug, adding microdoses provide a medicinal and therapeutic purpose for those suffering from various ailments.

He said it can also help treat stress associated with cancer, multiple sclerosis and other illnesses.

“The general feelings you will get is a reduction in anxiety, feelings of calmness and relaxation. It can help you sleep better. It can help you put your life, and maybe your problems, in a better perspective and it can alleviate a depression for people.”

But the sale of the psychedelic drug is still very much against the law in Canada.

“Mushrooms that contain the chemical psilocybin are illegal under the Federal Controlled Drugs and Substances Act, and the possession and trafficking of this drug is illegal,” a spokesperson with the Ministry of Public Safety and the Solicitor General said in an email statement. “Police will continue to investigate and submit cases for charge approval for those who prey on vulnerable people by selling illegal drugs.”

The Vancouver Police Department said it is aware of Larsen’s online shop and is looking into it.

“Magic mushrooms and other psychedelic drugs are not typically an enforcement priority for the VPD, given the ongoing opioid epidemic, unless there are aggravating factors such as trafficking to children, or near schools and playgrounds,” said Const. Steve Addison in an email.

Larsen plans on opening a brick-and-mortar shop in the next couple of months and has already started scouting for a spot.

But he knows there may be challenges with the City of Vancouver.

The city officials echo the sentiment from the province, saying the sale of psilocybe mushrooms are against the law.

“We do not have a licence category for this type of business,” said Chief Licence Inspector Kathryn Holm. “(It) is prohibited under federal statute and enforcement would be determined by the federal government.”

For now, Larsen is content cashing in the sales from his online store. Within five days of running it, he claims to already have 40 customers.

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If you want to buy magic truffles, you’re in the right place. Zamnesia has years of experience with psychedelics, so it’s no surprise we’re considered one of the best sources of magic truffles around. With products to suit first-time users and seasoned psychonauts, you can be certain you’ll find the perfect truffle variety for your needs and preferences.

WHAT ARE MAGIC TRUFFLES?

Magic truffles (technically known as sclerotia) are the subterranean part of certain types of psilocybin-containing mushrooms. Under Dutch law, psilocybin mushrooms are illegal, but psilocybin sclerotia are not, hence you can buy them legally.

Magic truffles contain the psychoactive compounds psilocybin and psilocin, which can cause powerful hallucinogenic experiences. These experiences can be deeply profound, and very exciting. Research is now looking into whether psilocybin might have some benefit in a medical setting, although it is too early to make claims about the results.

Truffles can also be used for microdosing, a practice in which people take regular, “sub-perceptual” doses. If you want to try this, we have specific magic truffle microdosing packs you can buy to make life easy for you.

THE STRONGEST MAGIC TRUFFLES

Not all truffles are created equal. For beginners, there are milder varieties that will produce a lighter, more manageable trip. For experienced psychonauts, we have highly potent truffles that will guarantee powerful trips.

Mexicana is our mildest truffle variety, but don’t think it’s not worth taking. Beginners will find Mexicana truffles suitably strong. If you purchase this pack, there’s little risk of experiencing an overwhelming trip. You can eat everything in there and have confidence that you’ll retain your faculties.

For the more experienced, Valhalla are the strongest truffles available. Exercise caution with these, as they can cause very intense trips. A whole pack will offer an incredible journey, as long as you approach it with respect.

HOW MANY GRAMS ARE IN A MAGIC TRUFFLE PACKET?

Almost all of our packs contain 15 grams of magic truffles. Depending on the strain and how high you want to get, this is usually enough for between 1 and 2 trips.

The Dynamic Duo pack contains 25 grams, and can be split between two people for a moderate to strong trip.

HOW TO STORE TRUFFLES

Magic truffles must be stored in the fridge, for a maximum of two months. Once opened, they should be consumed within two days.

It’s very important to keep them sealed and cold, otherwise they can turn bad pretty quickly!

HOW MANY GRAMS OF MAGIC TRUFFLES SHOULD YOU TAKE?

There is no single answer to this question. It depends on several factors, such as:

  • Previous experience with psilocybin
  • Body weight
  • Strain of truffle
  • What kind of experience you’re after

Generally, somewhere between 7 and 15 grams will be the right amount, though this is very general. Seven grams of Mexicana will be a pretty light trip, whereas 15 grams of Valhalla will be very powerful.

Check out our shroom and truffle dosage calculator for more information.

MAGIC MUSHROOM DOSAGE CALCULATORCALCULATE

CULTIVATING YOUR OWN TRUFFLES

If you love magic truffles so much that you want to cultivate your own, we can help get you started. Our magic truffle cultivation sets contain all that’s necessary to grow your own truffles in 12–20 weeks. And if you exercise patience, the flushes (harvests) can be pretty big! What’s more, you get three different strains in each set.

MAGIC TRUFFLES: QUESTIONS & ANSWERS

🥜 How to take magic truffles📦 How to store magic truffles⏲️ How long do vacuum-sealed magic truffles last?🍵 How to make magic truffle tea🏘️ Are magic truffles legal in Amsterdam?

VISIT ZAMNESIA FOR THE BEST MAGIC TRUFFLES AVAILABLE

If you want the very best magic truffles around, you can’t do any better than the Zamnesia Shroomshop. We have truffles ranging from fairly mild and perfect for beginners, to those that are incredibly strong and should be approached with due caution!

Whichever magic truffles you choose to buy, remember that set and setting are crucial to having a good experience. Be safe and have fun!

THE LEGALITY OF MAGIC MUSHROOMS IN CALIFORNIA

Psilocybe cubensis photographed in Xalapa, Veracruz, Mexico, by mycologist Alan Rockefeller.

California has been at the forefront of psychedelic policy change for years.  In 2019, the City of Oakland became “the first in the nation to decriminalize a wide range of psychedelics such as psilocybin mushrooms and ayahuasca.”  Similarly, in early 2020, city leaders in Santa Cruz unanimously agreed to “decriminalize the adult use, possession, and cultivation of entheogenic psychoactive plants and fungi.”  More broadly, Decriminalize California, a statewide grassroots effort to legalize psilocybin mushrooms in the Golden State via a voter initiative, picked up considerable momentum, but unfortunately stalled out after the outbreak of COVID-19 made the in-person collection of signatures practically impossible.

Most recently, on November 15, 2020, State Senator Scott Wiener tweeted, “It’s time to take a health/science based approach to drugs & move away from knee-jerk criminalization.  Psychedelics have medicinal benefits & they shouldn’t be illegal.  That’s why, when the Legislature reconvenes, we’ll work to decriminalize their use.”

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Senator Wiener’s tweet linked to a news article which discusses increasing numbers of patients and therapists coming out of the psychedelic closet.

“Magic mushrooms” as they are colloquially known, have been the focus of intense research in recent years.  In late 2018, Compass Pathway’s psilocybin treatment for treatment resistant depression received Breakthrough Therapy designation from the Food and Drug Administration.

The question remains: how illegal are “magic mushrooms” (defined as fungi containing the controlled substances psilocybin or psilocyn) under California law?  Is there a viable medical defense?  What about a religious defense?

Under California law, psilocybin and psilocyn, two active substances in “magic mushrooms,” are classified as Schedule I hallucinogenic controlled substances.

(d) Hallucinogenic substances. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation, which contains any quantity of the following hallucinogenic substances, or which contains any of its salts, isomers, and salts of isomers whenever the existence of those salts, isomers, and salts of isomers is possible within the specific chemical designation (for purposes of this subdivision only, the term “isomer” includes the optical, position, and geometric isomers):

California Health & Safety Code Section 11054, subdivision (d). There is no medical or religious exception in the statutes.

California law prohibits, as an alternate felony-misdemeanor or “wobbler”, the cultivation of “any spores or mycelium capable of producing mushrooms or other substance” containing psilocybin or psilocyn, if done with the intent of producing psilocybin or psilocyn.

California Health & Safety Code Section 11390.  This  means that, depending upon the circumstances, a person suspected of unlawful cultivation of mushrooms faces the possibility of a felony arrest and conviction with an exposure of up to three years in the state prison.

California Health & Safety Code Section 11391  similarly prohibits various types activity related to mushrooms, if done for the prohibited purpose of facilitating a violation of Section 11390.  Because of the intent requirement, the scope of Section 11391  is quite narrow, and this particular section by its terms does not prohibit the sales, possession for sales, and, transportation for sale of mushrooms or other material which contain psilocyn or psilocybin unless there is specific intent.  Depending on the circumstances, a person suspected of a violation of Section 11391 faces the possibility of a felony arrest and conviction with an exposure of up to three years in the state prison.

California Health & Safety Code Section 11392 provides a limited exception for “bona fide research, instruction, or analysis” provided such activity is: 1) “not in violation of federal law” and, 2)  “the research, instruction, or analysis is approved by the Research Advisory Panel  established pursuant  to Sections 11480 and 11481” of the Health and Safety Code.

Because psilocyn or psilocybin  are classified as Schedule I hallucinogenic controlled substances pursuant to Health and Safety Code Section 11054, subdivisions (d)(18) and (d)(19), any “material, compound, mixture, or preparation” containing psilocyn or psilocybin is subject to prosecution pursuant to another set of statutes applicable to Schedule I controlled substances under California’s Uniform Controlled Substances Act.

In particular, Health and Safety Code Section 11377 forbids the possession of any “material, compound, mixture, or preparation” containing psilocyn or psilocybin, which ordinarily is classified as a misdemeanor punishable by up to one year in the county jail unless the person has certain aggravating “priors.”  

Pursuant to Proposition 36, anyone charged with personal use, possession for personal use, or transportation for personal use of a controlled substance, may qualify for drug treatment instead of jail. The court must grant probation as an alternative to incarceration to qualifying defendants convicted of “nonviolent drug possession offenses,” as defined in Penal Code § 1210(a). Penal Code § 1210.1(a). Courts must impose, as a condition of probation, completion of a drug treatment program not to exceed 12 months, with optional aftercare of up to six months. The court may also require that the defendant participate in vocational training, family counseling, literacy training, and/or community service. Penal Code § 1210.1(a). Qualifying defendants must consent to participate in a drug treatment program, must be amenable to treatment, and must not otherwise be excluded from participation under Penal Code § 1210.1(b).

The scope of Proposition 36 is narrow and does not apply to sales-related offenses.  For example, Health and Safety Code Section 11378 forbids the possession for sale of any “material, compound, mixture, or preparation” containing psilocyn or psilocybin.  The crime is classified as a non-reducible felony subject to sentencing pursuant to Penal Code Section 1170(h), which generally means up to three years in the county jail.

Moreover, Health and Safety Code Section 11379 forbids numerous activities as felonies which are generally punishable by up to four years in the county jail.  Thus, anyone who “transports, imports into this state, sells, furnishes, administers, or gives away, or offers to transport, import into this state, sell, furnish, administer, or give away, or attempts to import into this state or transport” certain specified controlled substances (including any “material, compound, mixture, or preparation” containing psilocyn or psilocybin) faces substantial criminal exposure for conduct which constitutes a non-reducible felony under California law.

(a) Except as otherwise provided in subdivision (b) and in Article 7 (commencing with Section 4211) of Chapter 9 of Division 2 of the Business and Professions Code, every person who transports, imports into this state, sells, furnishes, administers, or gives away, or offers to transport, import into this state, sell, furnish, administer, or give away, or attempts to import into this state or transport any controlled substance which is (1) classified in Schedule III, IV, or V and which is not a narcotic drug, except subdivision (g) of Section 11056, (2) specified in subdivision (d) of Section 11054, except paragraphs (13), (14), (15), (20), (21), (22), and (23) of subdivision (d), (3) specified in paragraph (11) of subdivision (c) of Section 11056, (4) specified in paragraph (2) or (3) of subdivision (f) of Section 11054, or (5) specified in subdivision (d) or (e), except paragraph (3) of subdivision (e), or specified in subparagraph (A) of paragraph (1) of subdivision (f), of Section 11055, unless upon the prescription of a physician, dentist, podiatrist, or veterinarian, licensed to practice in this state, shall be punished by imprisonment pursuant to subdivision (h) of Section 1170 of the Penal Code for a period of two, three, or four years.
(b) Notwithstanding the penalty provisions of subdivision (a), any person who transports any controlled substances specified in subdivision (a) within this state from one county to another noncontiguous county shall be punished by imprisonment pursuant to subdivision (h) of Section 1170 of the Penal Code for three, six, or nine years. (c) For purposes of this section, “transports” means to transport for sale.

Additionally, subdivision (b) increases the criminal exposure to nine years for any person who transports controlled substances “within this state from one county to another noncontiguous county.”
This means, for example, that if a person were to transport for sale from one county to another any “material, compound, mixture, or preparation” containing psilocyn or psilocybin, and the counties are contiguous (meaning adjacent), the criminal exposure is a maximum of four years; however, if the counties are not contiguous (meaning the person travels through a total of three or more counties) the criminal exposure increases to a maximum of nine years in the county jail.

The case law interpreting Health and Safety Code Section 11379 is draconian.  For example, in People v. Patterson (1999) 72 Cal.App.4th 438, the Third Appellate District of the California Court of Appeal held that, in order to prove the offense of transportation of a controlled substance for sale between noncontiguous counties, the prosecution did not have to prove that defendant intended to facilitate the sale of the drug in the noncontiguous county.  The Court of Appeal rejected the defendant’s construction of the statute, which would “place an onerous burden upon law enforcement to identify the county in which a defendant who is transporting illegal drugs intends to sell them.” 72 Cal.App.4th at 445.

Let us consider the following thought experiment. A person travels by car from San Francisco to San Jose to sell a few dozen psilocybin chocolates.  The vehicle is pulled over for speeding on 280 near Sunnyvale.  The driver is nervous, and the officer starts asking lots of questions.  The person panics and blurts a confession: they were transporting psilocybin chocolates from San Francisco to San Jose to sell at cost .

Because the City and County of San Francisco is not contiguous with the County of Santa Clara (one has to travel through either San Mateo County or Alameda County), such transportation for sale would constitute a non-reducible felony punishable by three, six, or nine years in the county jail, depending on the circumstances.  It makes no difference that the person intended to sell the chocolates at cost; the law does not require that the seller intend to make a profit, only that the seller intend to make a sale.

Could there be a viable medical defense?  Possibly,  if one can establish medical necessity by showing that the person has no adequate alternatives to the charged conduct. Realistically, it would be an uphill battle given that criminal courts tend to be skeptical of the medical necessity defense.  For example, in People v. Trippett (1997) 56 Cal.App.4th 1532, the California Court of Appeal affirmed the trial court’s rejection of the medical necessity jury instruction requested by legendary activist Pebbles Trippet, reasoning that she was not entitled to a medical cannabis necessity defense because she failed to establish that she had no adequate alternatives as she could have taken prescription Marinol instead.

What about a religious defense?  As one can also read in the Trippett decision, criminal courts tend to be skeptical of the religious defense and treat such claims dismissively.  Absent express statutory protections, the religious defense is challenging given United States Supreme Court precedent such as Employment Division v. Smith, which held that the First Amendment does not require states to accommodate illegal acts performed in pursuit of religious beliefs, and City of Boerne v. Flores, which struck down the federal Religious Freedom Restoration Act as it applies to the states as an unconstitutional use of Congress’s enforcement powers.

A different approach would be to rely on the Free Exercise Clause of the California Constitution, which provides, in pertinent part:

Free exercise and enjoyment of religion without discrimination of preference are guaranteed.  This liberty of conscience does not excuse acts that are licentious or inconsistent with the peace and safety of the State.  The Legislature shall make no law respecting an establishment of religion.

California Constitution, Article I, section 4.

The Assembly Judiciary Committee of the California State Legislature has authored an extensive Background Paper summarizing California’s Free Exercise Clause case law, and distilling arguments concerning a proposal, Assembly Bill 1617, to augment existing protections via a California version of the Religious Freedom Restoration Act.  As the Background Paper notes, there is considerable ambiguity about the level of judicial scrutiny afforded by the Free Exercise Clause of the California Constitution.  The California Supreme Court has declined to decide the question of whether the compelling interest test applies when the Free Exercise Clause of the California Constitution is invoked, leaving open for a future day the question of the scope of state constitutional protections for the religious use of psilocyn and/or psilocybin.

In sum, the time has come to update the legal landscape pertaining to magic mushrooms in California, and we thank visionary legislators such as State Senator Wiener for envisioning a better future.  Hopefully, 2021 will be the year when exciting legislative proposals begin long-awaited changes in the laws that govern our relationship with our ancient fungal allies.

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This information is provided as a public educational service and is not intended as legal advice. For specific questions regarding psychedelics law in California, please contact the Law Offices of Omar Figueroa at 707-829-0215 or [email protected] to schedule a confidential legal consultation

MICRODOSING PSYCHEDELICS

Microdosing is the act of integrating sub-perceptual doses of psychedelics, such as LSD, san pedro, or psilocybin mushrooms, into your weekly routine for enhanced levels of creativity, energy, focus, and improved relational skills. When we say “sub-perceptual”, we mean that the tiny amounts used, usually less than 1/10th of a standard recreational dose, are so small that you won’t experience any strong psychedelic or hallucinogenic effects. What microdosers do notice are profoundly positive changes to how they think and feel, which is what’s driven the explosion of interest in this approach to working with psychedelics to support health and wellness.

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WHAT’S THE HISTORY OF MICRODOSING?

The deeper history of microdosing in ancient cultures is contested, with disagreement among researchers on just how prevalent it was. However, we think that cultures such as the Aztecs used low doses of psilocybin mushrooms for various purposes.

In more recent times, the story of microdosing as we know it begins with James Fadiman, Ph.D., and his 2011 book, The Psychedelic Explorer’s Guide: Safe, Therapeutic, and Sacred Journeys, which explores microdosing as a subculture of psychedelic use. In 2015, Fadiman gave a podcast interview with entrepreneur and author of The 4-Hour Work Week, Tim Ferriss, which introduced microdosing to thousands of his fans and attracted mainstream journalists’ attention. 

Ferriss wasn’t the only author to notice Fadiman’s work. Inspired by The Psychedelic Explorer’s Guide, Ayelet Waldman turned to microdosing to calm the mood swings playing havoc with her career and relationships. The results were profoundly positive and became the core of her 2016 book, A Really Good Day: How Microdosing Made a Mega Difference in my Mood, My Marriage, and My Life

Mycologist and psilocybin-enthusiast Paul Stamets has also had a hand in pushing microdosing into the mainstream. One of the most reputable, decorated, and self-practiced mycologists in the world, Stamets has dedicated his life to the study of medicinal and psychedelic fungi. His most recent patent application is for a nootropic stack (a combination of cognitive enhancers) that contains a microdose of psilocybin, Lion’s Mane mushrooms, and niacin. He would like to see this supplement available as a vitamin, claiming that its efficacy in epigenetic neurogenesis has the potential to initiate “the next quantum leap in human consciousness.”

Now microdosing has hundreds of thousands of proponents worldwide—the r/microdosing subreddit alone has almost 150,000 users. No longer limited to Silicon Valley biohackers, people from all walks of life use microdosing to improve their mental health, creativity, and well-being.

MICRODOSING GUIDES

LSD and psilocybin mushrooms (“magic mushrooms”) are the two most common substances used for microdosing. However, microdosing can be done with nearly any psychedelic. The particular protocols for each will vary for things like preparation and dosage, so it’s important to learn as much as possible about whichever psychedelic you choose to microdose.

To that end, we’ve developed in-depth guides for microdosing several different psychedelics.

Each guide provides an overview of each psychedelic and includes topics such as History, Science & Research, How-To Guides including preparation and dosages, Benefits & Risks, FAQ’s, and Resource Articles.

Microdosing 1P‑LSD molecule illustration
Microdosing 1P‑LSD molecule illustration

MICRODOSING 1P‑LSDMICRODOSING 4‑ACO‑DMTMICRODOSING AYAHUASCAMICRODOSING DMTMICRODOSING IBOGAINEMICRODOSING LSDMICRODOSING MARIJUANAMICRODOSING MESCALINEMICRODOSING PSILOCYBIN MUSHROOMSMICRODOSING WITH PSILOCYBIN TRUFFLES

WHAT ARE THE BEST SUBSTANCES FOR MICRODOSING?

If a substance is psychoactive, you can be sure that someone has microdosed it. People have tried microdosing mescaline, N,N-dimethyltryptamine (DMT), ayahuasca, LSA, 2-CB, cannabis, ibogaine, ketamine, and pretty much anything else you could think of. But the two most commonly used, well-researched, plus most ethically and sustainably-produced substances for microdosing are lysergic acid diethylamide (LSD) and psilocybin.

MICRODOSING LSD

Microdosing with LSD is a fairly straightforward process. Essentially, you need to prepare your microdoses by volumetric dilution, consume the microdose at the appropriate time, and follow a month-long protocol to maximize your benefits. A standard protocol would be to microdose ten micrograms every third day, i.e., one day on, two days off in between. An essential part of this is what Fadiman called “observation”, where you keep a journal of thoughts, feelings, and bodily sensations that come up for you while microdosing. This practice allows you to become more aware of your progress and build a positive self-reflection habit. We also recommend that you take periodic breaks from microdosing altogether every six to eight weeks to evaluate your experience and avoid building up a tolerance to the practice.

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MICRODOSING PSILOCYBIN

Preparing psilocybin mushrooms or psilocybin truffles for microdosing involves more steps than microdosing with LSD but is still straightforward. The trickiest part is estimating how much psilocybin is in a particular mushroom. Different species and strains of mushrooms will not only have different quantities of psilocybin, but fresh and dried psilocybin mushrooms do, too. Even different parts of the mushroom can contain slightly different amounts. 

For Psilocybe cubensis, the classic magic mushroom, a typical microdose is 0.1 to 0.3 grams, although that amount may be smaller for people with clinical issues. Psilocybin truffles are usually milder, so you may require a slightly higher dose. Many wood-loving psilocybin mushrooms, such as Psilocybe cyanescens, are stronger, so you would need to take less. 

Once your doses are prepared by grinding to a powder and encapsulating, you can follow a similar protocol to that used for LSD, use the Stamets stack and dosing regimen, or work with us to develop your own protocol via our Microdosing Course or coaching services.  

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HOW SHOULD I PROPERLY MICRODOSE CANNABIS?

Microdosing cannabis is relatively easy, once you find your ideal dose. While it’s possible to microdose cannabis by smoking or vaping, we’ve found that the simplest and most reliable method is by using low-dose edibles. The Marijuana Policy Project has designated 10mg of THC as a standard dose per serving, so anything below that can be considered low-dose. 

Products that call themselves low-dose tend to be in the 1mg to 5mg of THC range. We tend to recommend 2.5mg as a good starting point for microdosing, but always experiment to see what is best for you. Potency levels vary greatly between products and brands, and everyone’s personal tolerance level is unique. As a general rule, it’s best to take it slow and steady. After taking a microdose, wait at least two hours to see the full effects before taking more. This precaution is crucial with edibles, as they can take a relatively long time to take effect.

It is also not uncommon to hear of people microdosing CBD in conjunction with microdosing psilocybin mushrooms.

SHOULD I MICRODOSE MDMA?

Microdosing MDMA is not as common as LSD and psilocybin, but with the general rise in interest in microdosing, some have wondered if the practice could enhance their mood and boost their energy. While some people have reported success with an MDMA regimen, we do not recommend it. There’s a lot of evidence to suggest that frequent MDMA use can be detrimental to your health. After all, MDMA is not like classic psychedelics; it’s an amphetamine and a stimulant that does very different things to your body and neurochemistry than a tab or microdose of LSD.

HOW CAN I BE SURE I AM MICRODOSING SAFELY?

Apart from legality, the key factors around safe microdosing are substance, dosage, and effects.

  • Substance: Is this psychedelic what I think it is? Where legal, source your psychedelics from reputable suppliers. If this isn’t an option, ensure your substance is pure by using free drug-checking services or test kits to make sure you have unadulterated LSD rather than 25I-NBOMe or 2,5-Dimethoxy-4-iodoamphetamine (DOI). If you are using psilocybin, make sure your mushrooms are the correct species by learning to identify them or only sourcing them from someone who can reliably do so. For mushroom sourcing tips and reliable vendor recommendations, check out Third Wave’s Ultimate Guide to Sourcing Psychedelic Medicines.
  • Dosage: Carefully measure your microdose using accurate scales for mushrooms, or by diluting your LSD so that it’s practical to take a small amount. Be aware that the strength of any psychedelic, natural or not, can vary. Some mushrooms are stronger than others, and one blotter can contain more LSD than the last.
  • Effects: While microdosing should be sub-perpetual enough to avoid interfering with your everyday life, be aware of how you are feeling and perceiving on days that you have dosed. Do not drive or operate heavy machinery while adversely affected! Pay attention to any adverse changes in mood or other unwanted side effects. These are signs that you might need to pause or adjust your protocol.
  • It’s Illegal (29.5% of reports) – One of the most frequently cited concerns about microdosing is that it’s illegal. While the cultural, poltical, and legal landscape continues to shift in a favorable direction for some psychedelic substances, this remains a concern for many.
  • Physiological discomfort (18.0%) – Includes disrupted senses (visual), temperature dysregulation, numbing/tingling, insomnia, gastrointestinal distress, reduced appetite, and increased migraines and/or headaches for some.
  • Impaired focus (8.8%) – Some reported poor focus, distractibility, and absent-mindedness.
  • Increased anxiety (6.7%) – General, social, and existential.
  • Impaired energy (7.2%) – Both excessive energy (restlessness, jitters) and inadequate energy (fatigue, drowsiness, brain fog).
  • Impaired mood (6.9%) – Mood deterioration (sadness, discontent, irritability), emotional difficulties (over-emotionality, mood swings), and impaired outlook (fear, feeling unusual).
  • Social interference (2.6%) – Awkwardness, oversharing, and difficulties with sentence-production in social settings.
  • Cognitive interference (2.3%) – Confusion, disorientation, racing thoughts, and poor memory.
  • Self-interference (1.2%) – Self-processing concerns (dissociation, depersonalization) and self-sabotaging (rumination, over-analysis).
  • Increased symptoms (other) (6.2%,) – After-effects (psychological dependence and concerns about potential addiction, substance tolerance, comedown or hangover) and also more concerning, but rare, adverse psychological events (0.7%).

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CAN I MICRODOSE FOR MY MENTAL HEALTH?

Recent research has shown that LSD and psilocybin can be highly effective in alleviating treatment-resistant depression. So it’s no surprise that people microdose to improve mental health. If this is your reason for exploring microdosing, it’s important to pay attention to any changes in your moods and thoughts, as this will maximize your benefit and make it easier to know if you need to tweak your protocol. As with any medical or psychological condition that you might have concerns about, if you have serious mental health issues, we recommend seeking advice from an appropriate medical health professional.

Are you feeling drawn to work with plant medicines for mental health? Third Wave’s vetted Psychedelic Directory offers an honest, in-depth guide to safely access these substances.

CAN I MICRODOSE FOR CREATIVITY?

Some people find they get the biggest boost to creativity on the days they microdose; others feel the most benefit in the days after. Either way, the key here is to figure out when you will feel this and then integrate your creative practice accordingly. There is no one-size-fits-all rule for what helps us be more creative. But by following a microdosing protocol and being mindful of thoughts and feelings, you can discover what works best for you.

CAN I MICRODOSE FOR OVERALL WELL BEING?

Even though we sometimes think of mental and physical well-being as separate, they’re very interconnected. When your mood is better, or you’re less stressed, your body will thank you! In that sense, any microdosing practice that is good for your mind will tend to be positive for you overall. The trick to maximizing this is self-reflection so that you can become aware of what factors enhance your well-being, as well as those that might hold you back. This can sound hard. Luckily, microdosing can boost the effectiveness of mindfulness, and we’re always ready to help you upskill to get the most from your microdosing journey.

CHOOSING A PSYCHEDELIC RETREAT IS A BIG DECISION. CHOOSE WISELY.Explore our trusted network of psychedelic retreat centers in the free Third Wave Directory. Compare facilities, participant reviews, and pricing to find the right fit for your unique needs.

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WHAT’S THE SUPPORTING SCIENCE BEHIND MICRODOSING?

Even though clinical trials on psychedelics are ongoing, the basic neuroscience of how they interact with our brains is well-established. Much of what we understand about how psychedelics work involves serotonin, a chemical that is among the brain’s most important neurotransmitters. Serotonin affects nearly everything we do, from how we feel to how we digest our food. Psychedelics such as LSD and psilocybin share a similar structure to serotonin and mimic the chemical’s effects. 

Because serotonin is so important to mood stabilization, common antidepressants (called Selective Serotonin Reuptake Inhibitors, or SSRIs) increase serotonin levels in the brain, which can make you feel happier.

Psychedelics work more directly by mimicking serotonin. One of psilocybin’s main effects is to stimulate a serotonin receptor called “5-HT2A” located in the prefrontal cortex, which leads to two important results:

These effects have spurred an explosion of research into the psychopharmacology of psychedelics in recent years. Scientists are investigating psychedelic-assisted psychotherapy to alleviate conditions such as ADHD, depression, anxiety, obsessive-compulsive disorder, post-traumatic stress disorder, and substance use disorder. If successful, these therapies could profoundly change the practice of modern psychiatry.

Compared to higher doses of psychedelic drugs, there has been relatively little scientific research into microdosing. But this is rapidly changing as well, with more peer-reviewed articles published about microdosing in 2020 than there had been in the entire previous decade. 

Participants in microdosing research consistently report improvements to cognition and mood, and multiple studies have found that microdosers experience increases in creativity. A 2019 systematic study of microdosing found that it led to longer-term improved mental health and improved concentration. Interestingly this same study found that microdosers’ expectations didn’t alter their experiences, suggesting the benefits of microdosing aren’t just a placebo effect.

Like full doses, microdoses of psychedelics appear to encourage neuron growth, so we can expect future research to branch out into investigating new treatments for Alzheimer’s disease and dementia, and companies such as Eleusis are already pursuing this. Recent research also indicates that low doses of LSD can reduce perceptions of discomfort, suggesting the potential for a whole new approach to pain relief

WHAT ARE THE POSITIVE EFFECTS OF MICRODOSING?

According to a study in the Harm Reduction Journal, the benefits of microdosing include:

  • Improved mood (26.6%) – Peacefulness, overall well-being, calmness, happiness, and a reduction in the symptoms of depression. This includes more emotional connection, a general sense of optimism, and an improved outlook on life.
  • Improved focus (14.8%) – Covers skill sets like the ability to focus or concentrate and enhanced self-awareness.
  • Creativity (12.9%) – Aside from a general sense of improved creativity, this also includes behaviors such as being more open, enhanced curiosity, ability to shift perspectives, and divergent thinking.
  • Self-efficacy (11.3%) – This applies to such behaviors as ambition, self-motivation, self-confidence, and a sense of agency. It also relates to improved mental health, including increased introspection, the practice of meditation, and other aspects of behaviors tied to self-care.
  • Improved energy (10.5%) – In this case, “energy” refers to things like mental stimulation, wakefulness, and alertness.
  • Social benefits (7.6%) – Outside of more engagement with others, this category also includes more empathy, a greater sense of connection, and more extroversion.
  • Cognitive benefits (5.8%) – When microdosing, users experience heightened mental clarity, better memory recall, and improved problem-solving ability.
  • Reduced anxiety (4.2%) – This applies to a reduction in both general and social anxiety.
  • Physiological enhancement (3.0%) – Includes enhanced visual acuity, cardio endurance, reduction of migraines and headaches, and higher sleep quality.

In helping people learn how to microdose, the feedback we’ve received via participant questionnaires tells a similar story. Participants in our programs frequently report improvements in their mental health, creativity, and cognition.  

“When microdosing, I observed several benefits, including reduced social anxiety, better confidence when leading groups, the further flourishing of my writing practice, enhanced creativity, and courage on a day-to-day basis. Third Wave’s program gave excellent guidance on how to properly microdose with LSD and mushrooms. Personally, I enjoyed the journaling aspect the most.” –Miki L, Writer

WHAT’S THE BENEFIT OF MICRODOSING VS MACRODOSING

If a microdose involves taking a small amount of a hallucinogenic substance, macrodosing is just the opposite—taking a dose that will produce profound emotional, perceptual, and even spiritual effects. It isn’t the case that one approach is better than the other. They serve different purposes, and you choose them for different reasons. 

The benefits of microdosing are subtle and build up over time. You won’t have the same experiences when microdosing as you could have with a fully psychedelic dose. But microdosing is easier to fit into your weekly schedule, and integrating is much less challenging—there is typically no chance of a “bad trip” or experience when done properly. 

Some people find that microdosing is a good way to develop their relationship with a psychedelic drug and get a feel for how it interacts with their unique brain and body chemistry before taking the more daunting step of a full macrodose. There is also growing interest in using microdosing to help integrate the psychedelic insights from high-dose experiences.

POTENTIAL NEGATIVE EFFECTS OF MICRODOSING

If you aren’t careful in measuring your microdose, you might end up taking more than intended. While this is highly unlikely to cause you any ongoing problems, it can be extremely inconvenient if you intended to have a solid day of work but instead find yourself being one with the Earth. 

More seriously, even small doses of psychedelics can amplify current emotions and mental states, so assessing your mindset is always important. This amplification means that if you have schizophrenia or bipolar disorder, it is essential you discuss the risks with a medical professional before microdosing. 

Since there has been relatively limited scientific research on the safety of microdosing, it’s best to avoid doing it for extended periods (longer than a few months). In fact, chronic microdosing does come with potential heart risk, though there is reason to believe that this may be relatively minor.

Other potential negative side effects and challenges that microdosers have reported include:

The 6 Risks of Microdosing
  • It’s Illegal (29.5% of reports) – One of the most frequently cited concerns about microdosing is that it’s illegal. While the cultural, poltical, and legal landscape continues to shift in a favorable direction for some psychedelic substances, this remains a concern for many.
  • Physiological discomfort (18.0%) – Includes disrupted senses (visual), temperature dysregulation, numbing/tingling, insomnia, gastrointestinal distress, reduced appetite, and increased migraines and/or headaches for some.
  • Impaired focus (8.8%) – Some reported poor focus, distractibility, and absent-mindedness.
  • Increased anxiety (6.7%) – General, social, and existential.
  • Impaired energy (7.2%) – Both excessive energy (restlessness, jitters) and inadequate energy (fatigue, drowsiness, brain fog).
  • Impaired mood (6.9%) – Mood deterioration (sadness, discontent, irritability), emotional difficulties (over-emotionality, mood swings), and impaired outlook (fear, feeling unusual).
  • Social interference (2.6%) – Awkwardness, oversharing, and difficulties with sentence-production in social settings.
  • Cognitive interference (2.3%) – Confusion, disorientation, racing thoughts, and poor memory.
  • Self-interference (1.2%) – Self-processing concerns (dissociation, depersonalization) and self-sabotaging (rumination, over-analysis).
  • Increased symptoms (other) (6.2%,) – After-effects (psychological dependence and concerns about potential addiction, substance tolerance, comedown or hangover) and also more concerning, but rare, adverse psychological events (0.7%).

CAN I MICRODOSE FOR MY MENTAL HEALTH?

Recent research has shown that LSD and psilocybin can be highly effective in alleviating treatment-resistant depression. So it’s no surprise that people microdose to improve mental health. If this is your reason for exploring microdosing, it’s important to pay attention to any changes in your moods and thoughts, as this will maximize your benefit and make it easier to know if you need to tweak your protocol. As with any medical or psychological condition that you might have concerns about, if you have serious mental health issues, we recommend seeking advice from an appropriate medical health professional.

CAN I MICRODOSE FOR CREATIVITY?

Some people find they get the biggest boost to creativity on the days they microdose; others feel the most benefit in the days after. Either way, the key here is to figure out when you will feel this and then integrate your creative practice accordingly. There is no one-size-fits-all rule for what helps us be more creative. But by following a microdosing protocol and being mindful of thoughts and feelings, you can discover what works best for you.

CAN I MICRODOSE FOR OVERALL WELL BEING?

Even though we sometimes think of mental and physical well-being as separate, they’re very interconnected. When your mood is better, or you’re less stressed, your body will thank you! In that sense, any microdosing practice that is good for your mind will tend to be positive for you overall. The trick to maximizing this is self-reflection so that you can become aware of what factors enhance your well-being, as well as those that might hold you back. This can sound hard. Luckily, microdosing can boost the effectiveness of mindfulness, and we’re always ready to help you upskill to get the most from your microdosing journey.

OUR MICRODOSING COURSE

Third Wave’s Microdosing Course is an in-depth online course that will teach you all the ins and outs of microdosing, with a particular focus on how you can harness this cutting-edge technology to live a better life.

  • How do I get the substance safely and legally?
  • Once I get it, how do I prepare it?
  • Once I prepare it, how do I best utilize it?

Learn About Our Microdosing Courses

microdosing course mockup

MICRODOSING PROTOCOL

Here is a basic overview of the microdosing protocol laid out by James Fadiman, Ph.D., based on microdosing research he has carried out since 2012.

This protocol can be used to microdose LSD or psilocybin mushrooms.

  1. Dosing – A true microdose (or low dose) in which the effects are sub-perceptual is about 1/10th of a standard dose, although this varies on an individual basis. Typically, a standard ldose of LSD is 100 micrograms, meaning a microdose is 10 micrograms. For psilocybin, a standard dose is 3.5 grams of dried mushrooms. Thus, a microdose of mushrooms is between .1 to .3 grams.
  2. Observation – Throughout the day, track your experience by journaling. Note any changes in mood, perception, mental state, or feelings that arise on your microdosing day and the day after.
  3. Calibration – Many factors contribute to calibrating the proper dose level, including body composition, mental state, and experience with psychedelics. When calibrating, make incremental changes in the amount you take. This will help to optimize the experience.
  4. Timing – Dr. Fadiman’s protocol calls for one day on, two days off, one day on, two days off. If the first dose is taken on Monday, wait until Thursday to take the following dose. Pause your protocol after microdosing for 6-8 weeks to evaluate the impact of the experience so you can adjust as needed. Breaks are also important so you don’t build up a tolerance to microdosing.

IS MICRODOSING LEGAL?

Microdosing is only as legal as the psychedelic fungi or substances you’re working with, in the country or state where you’re working with them. This means that, in most places, microdosing LSD remains illegal (despite its excellent safety profile and therapeutic efficacy). While we support changing the laws that create this situation, we do not recommend breaking them. Knowing the law where you are is vital for avoiding legal difficulties and finding the least legally problematic options.

Accessing quality psilocybin mushrooms can seem challenging, especially when you’re unsure of the local laws or how to choose a reputable vendor. That’s why we compiled our tips and resources into the Ultimate Guide to Sourcing Psychedelic Medicines.

MICRODOSING RESEARCH

The third wave of psychedelics is possible because of the work of researchers across the globe. Organizations like MAPS, The Beckley Foundation, Heffter Research Institute, Johns Hopkins, Usona and others are paving the way for a new paradigm in mental health.

To date, clinical trials are not yet being conducted on the effects of microdosing, though some studies are in the works.

Below are a few of the key non-clinical studies which demonstrate the benefits of microdosing psychedelics:

The Beckley Foundation is leading the charge, where they are administering several placebo-controlled microdosing studies. An area of focus for this research is the therapeutic benefits of taking low doses of LSD. This microdosing study will allow scientists to determine if there is evidence to support the idea that psychedelic drugs affect brain activity, mood, creativity, and cognition.

HOW CAN I CREATE LASTING CHANGE WITH MICRODOSING?

Whatever your goals, the best way to create lasting change with microdosing is to mindfully pay attention to the changes you experience when doing it and consciously create new and positive habits. This is why the “observation” step in Fadiman’s microdosing protocol is so important. 

Because microdosing can enhance our ability to create new neural pathways, it gives us a great opportunity to gradually learn to think and act in ways that allow us to live more fulfilling lives and experience greater well-being. The subjective effects of taking a microdose fade, but the positive changes to your brain that come from the conscious cultivation of constructive ways of thinking and working will last for much longer. 

HOW CAN THIRD WAVE SUPPORT ME ON MY MICRODOSING JOURNEY?

As well as our extensive collection of guides to microdosing different substances near the top of this guide, Third Wave offers a range of ways to enhance your microdosing experience. By connecting you with experts who have specialist skills, knowledge, and experience, you’ll learn how to microdose in the right way for your unique situation. 

Based on Dr. Fadiman’s work and enhanced by feedback from over 3,000 participants, our Microdosing Course outdoes the one-size-fits-all model by giving you step-by-step instructions to personalize your microdosing experience to your unique body, goals, and situation.

We can also connect you with experienced microdosing coaches who can provide personalized guidance, feedback, and mentoring to help you reach your goals and set you up for lasting success.

And, if you’re looking for the ultimate in microdosing education and support, you can join the Microdosing Experience, a live six-week immersion program using microdosing, intention, and breathwork as tools for accelerated growth. The feedback from participants has been overwhelmingly positive, so we would love to be with you on this part of your journey. 

microdosing psychedelics book cover front

ng a second look at psychedelics.

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